Calibrate vs Fifty 410: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Calibrate starts at $199/mo and Fifty 410 at $166/mo. Calibrate scores higher on our ClearScore (76 vs 68), and Fifty 410 is the cheaper starting option.
Quick Verdict
Calibrate has the higher ClearScore (76 vs 68)
Fifty 410 is more affordable ($166/mo vs $199/mo)
Fifty 410 has higher ratings (4.5/5 vs 4.3/5)
Fifty 410 scores better on value (4.3/5 vs 3.8/5)
Calibrate
$199/mo
starting price
Year-long metabolic reset with dedicated coaching, GLP-1 medication, and a structured curriculum covering all lifestyle factors.
Fifty 410
$166/mo
starting price
Multi-month discounts on tirzepatide. 4.9 Trustpilot rating (2,847 reviews). Uses 503A and 503B pharmacies.
Calibrate vs Fifty 410: Full Comparison
| Calibrate | Fifty 410 | |
|---|---|---|
| ClearScore | 76/100 ✓ | 68/100 |
| Overall Rating | 4.3/5 | 4.5/5 ✓ |
| Review Count | 74 | 2,847 ✓ |
| Starting Price | $199/mo | $166/mo ✓ |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 2023 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Calibrate Programs
Metabolic Reset
$199/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Dedicated Coach
- Metabolic Curriculum
- Lab Work
Fifty 410 Programs
Semaglutide (4 weeks)
$199/mo
Medications: Compounded Semaglutide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (4 weeks)
$299/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (3-month plan)
From $166/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Ratings Breakdown
| Category | Calibrate | Fifty 410 |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Calibrate edges out Fifty 410 with a ClearScore of 76 vs 68. Fifty 410 is more affordable starting at $166/mo compared to $199/mo. For customer support, Calibrate rates higher (4.7/5). The best choice depends on your priorities, medication preferences, and budget.