Calibrate vs Mayo Clinic Diet: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Mayo Clinic Diet has the higher ClearScore (78 vs 76)
Mayo Clinic Diet is more affordable ($50/mo vs $159/mo)
Mayo Clinic Diet has higher ratings (4.4/5 vs 4.3/5)
Calibrate
$159/mo
starting price
Year-long metabolic reset with dedicated coaching, GLP-1 medication, and a structured curriculum covering all lifestyle factors.
Mayo Clinic Diet
$50/mo
starting price
World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.
Calibrate vs Mayo Clinic Diet: Full Comparison
| Calibrate | Mayo Clinic Diet | |
|---|---|---|
| ClearScore | 76/100 | 78/100 ✓ |
| Overall Rating | 4.3/5 | 4.4/5 ✓ |
| Review Count | 74 | 98 ✓ |
| Starting Price | $159/mo | $50/mo ✓ |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide ✓ |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 1889 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Calibrate Programs
Metabolic Reset
$159/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Dedicated Coach
- Metabolic Curriculum
- Lab Work
Mayo Clinic Diet Programs
Companion Subscription
$49.99/mo (diet support only)
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
Clinical Subscription
$99.99/mo + $99.99 start fee + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Visits Via Amwell
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
- Exercise Program
Ratings Breakdown
| Category | Calibrate | Mayo Clinic Diet |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Mayo Clinic Diet edges out Calibrate with a ClearScore of 78 vs 76. Mayo Clinic Diet is more affordable starting at $50/mo compared to $159/mo. For customer support, Calibrate rates higher (4.7/5). The best choice depends on your priorities, medication preferences, and budget.