Calibrate vs Profile by Sanford: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Calibrate is more affordable ($159/mo vs $279/mo)
Profile by Sanford scores better on value (3.9/5 vs 3.8/5)
Calibrate
$159/mo
starting price
Year-long metabolic reset with dedicated coaching, GLP-1 medication, and a structured curriculum covering all lifestyle factors.
Profile by Sanford
$279/mo
starting price
Backed by Sanford Health system. Physician-designed GLP-1 programs with nutrition coaching and meal planning at clinics across the Midwest.
Calibrate vs Profile by Sanford: Full Comparison
| Calibrate | Profile by Sanford | |
|---|---|---|
| ClearScore | 76/100 | 76/100 |
| Overall Rating | 4.3/5 | 4.3/5 |
| Review Count | 74 | 157 ✓ |
| Starting Price | $159/mo ✓ | $279/mo |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Branded Semaglutide, Branded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 2012 |
| States Served | All 50 states | 9 states |
Programs & Pricing
Calibrate Programs
Metabolic Reset
$159/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Dedicated Coach
- Metabolic Curriculum
- Lab Work
Profile by Sanford Programs
Profile Program with GLP-1
$279/mo
Medications: Branded Semaglutide, Branded Tirzepatide
- Medication
- Nutrition Coaching
- Meal Planning
- Progress Check Ins
- Health System Backing
Ratings Breakdown
| Category | Calibrate | Profile by Sanford |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Calibrate and Profile by Sanford are closely matched with ClearScores of 76. Calibrate is more affordable starting at $159/mo compared to $279/mo. For customer support, Calibrate rates higher (4.7/5). The best choice depends on your priorities, medication preferences, and budget.