Calibrate vs SkyRx: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Calibrate has the higher ClearScore (76 vs 75)
Calibrate is more affordable ($159/mo vs $299/mo)
SkyRx has higher ratings (4.4/5 vs 4.3/5)
Calibrate scores better on value (3.8/5 vs 3.6/5)
Calibrate
$159/mo
starting price
Year-long metabolic reset with dedicated coaching, GLP-1 medication, and a structured curriculum covering all lifestyle factors.
SkyRx
$299/mo
starting price
Premium GLP-1 program with full labs, high-touch clinician access, and both semaglutide and tirzepatide.
Calibrate vs SkyRx: Full Comparison
| Calibrate | SkyRx | |
|---|---|---|
| ClearScore | 76/100 ✓ | 75/100 |
| Overall Rating | 4.3/5 | 4.4/5 ✓ |
| Review Count | 74 ✓ | 58 |
| Starting Price | $159/mo ✓ | $299/mo |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 2022 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Calibrate Programs
Metabolic Reset
$159/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Dedicated Coach
- Metabolic Curriculum
- Lab Work
SkyRx Programs
Premium Weight Loss
$299/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Full Labs
- Dedicated Clinician
- Priority Support
Ratings Breakdown
| Category | Calibrate | SkyRx |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Calibrate edges out SkyRx with a ClearScore of 76 vs 75. Calibrate is more affordable starting at $159/mo compared to $299/mo. For customer support, SkyRx rates higher (4.8/5). The best choice depends on your priorities, medication preferences, and budget.