Fifty 410 vs HormoneSynergy: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Fifty 410 starts at $166/mo and HormoneSynergy at $300/mo. HormoneSynergy scores higher on our ClearScore (68 vs 70), and Fifty 410 is the cheaper starting option.
Quick Verdict
HormoneSynergy has the higher ClearScore (70 vs 68)
Fifty 410 is more affordable ($166/mo vs $300/mo)
HormoneSynergy has higher ratings (4.6/5 vs 4.5/5)
Fifty 410 scores better on value (4.3/5 vs 4.1/5)
Fifty 410
$166/mo
starting price
Multi-month discounts on tirzepatide. 4.9 Trustpilot rating (2,847 reviews). Uses 503A and 503B pharmacies.
HormoneSynergy
$300/mo
starting price
Longevity-focused GLP-1 program with DEXA scans, CGM, and hormone optimization in Portland, OR.
Fifty 410 vs HormoneSynergy: Full Comparison
| Fifty 410 | HormoneSynergy | |
|---|---|---|
| ClearScore | 68/100 | 70/100 ✓ |
| Overall Rating | 4.5/5 | 4.6/5 ✓ |
| Review Count | 2,847 ✓ | 42 |
| Starting Price | $166/mo ✓ | $300/mo |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Semaglutide, Tirzepatide |
| Telehealth | Yes | No |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Not accepted |
| Founded | 2023 | 2006 |
| States Served | All 50 states | 1 states |
Programs & Pricing
Fifty 410 Programs
Semaglutide (4 weeks)
$199/mo
Medications: Compounded Semaglutide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (4 weeks)
$299/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (3-month plan)
From $166/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
HormoneSynergy Programs
Weight Loss for Longevity
From $300/mo
Medications: Semaglutide, Tirzepatide
- Medication
- Dexa Scans
- Cgm Monitoring
- Hormone Optimization
Ratings Breakdown
| Category | Fifty 410 | HormoneSynergy |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
HormoneSynergy edges out Fifty 410 with a ClearScore of 70 vs 68. Fifty 410 is more affordable starting at $166/mo compared to $300/mo. For customer support, HormoneSynergy rates higher (4.7/5). The best choice depends on your priorities, medication preferences, and budget.