Fifty 410 vs Physicians Weight Loss Centers: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Fifty 410 starts at $166/mo and Physicians Weight Loss Centers at $299/mo. Physicians Weight Loss Centers scores higher on our ClearScore (68 vs 72), and Fifty 410 is the cheaper starting option.
Quick Verdict
Physicians Weight Loss Centers has the higher ClearScore (72 vs 68)
Fifty 410 is more affordable ($166/mo vs $299/mo)
Fifty 410 has higher ratings (4.5/5 vs 4.1/5)
Fifty 410 scores better on value (4.3/5 vs 3.8/5)
Fifty 410
$166/mo
starting price
Multi-month discounts on tirzepatide. 4.9 Trustpilot rating (2,847 reviews). Uses 503A and 503B pharmacies.
Physicians Weight Loss Centers
$299/mo
starting price
National franchise with clinics across the East Coast offering physician-supervised GLP-1 programs with weekly check-ins and meal plans.
Fifty 410 vs Physicians Weight Loss Centers: Full Comparison
| Fifty 410 | Physicians Weight Loss Centers | |
|---|---|---|
| ClearScore | 68/100 | 72/100 ✓ |
| Overall Rating | 4.5/5 ✓ | 4.1/5 |
| Review Count | 2,847 ✓ | 189 |
| Starting Price | $166/mo ✓ | $299/mo |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Branded Semaglutide, Branded Tirzepatide |
| Telehealth | Yes | No |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2023 | 1986 |
| States Served | All 50 states | 12 states |
Programs & Pricing
Fifty 410 Programs
Semaglutide (4 weeks)
$199/mo
Medications: Compounded Semaglutide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (4 weeks)
$299/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (3-month plan)
From $166/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Physicians Weight Loss Centers Programs
GLP-1 Weight Loss Program
$299/mo
Medications: Branded Semaglutide, Branded Tirzepatide
- Medication
- Weekly Check Ins
- Body Composition
- Personalized Meal Plan
Ratings Breakdown
| Category | Fifty 410 | Physicians Weight Loss Centers |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Physicians Weight Loss Centers edges out Fifty 410 with a ClearScore of 72 vs 68. Fifty 410 is more affordable starting at $166/mo compared to $299/mo. For customer support, Fifty 410 rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.