Hone Health vs Mayo Clinic Diet: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Hone Health starts at $185/mo and Mayo Clinic Diet at $50/mo. Mayo Clinic Diet scores higher on our ClearScore (77 vs 78), and Mayo Clinic Diet is the cheaper starting option.
Quick Verdict
Mayo Clinic Diet has the higher ClearScore (78 vs 77)
Mayo Clinic Diet is more affordable ($50/mo vs $185/mo)
Mayo Clinic Diet has higher ratings (4.4/5 vs 4.3/5)
Mayo Clinic Diet scores better on value (3.8/5 vs 3.3/5)
Hone Health
$185/mo
starting price
Lab-first GLP-1 prescribing plus hormone optimization. Compounded tirzepatide from $349/mo. $33M Series A.
Mayo Clinic Diet
$50/mo
starting price
World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.
Hone Health vs Mayo Clinic Diet: Full Comparison
| Hone Health | Mayo Clinic Diet | |
|---|---|---|
| ClearScore | 77/100 | 78/100 ✓ |
| Overall Rating | 4.3/5 | 4.4/5 ✓ |
| Review Count | 10,400 ✓ | 98 |
| Starting Price | $185/mo | $50/mo ✓ |
| Medications | Compounded Tirzepatide, Compounded Liraglutide | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide ✓ |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Not accepted | Accepted |
| Founded | 2018 | 1889 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Hone Health Programs
Liraglutide Program
$185/mo total
Medications: Compounded Liraglutide
- Medication
- Membership
- Lab Work
- Clinician Access
Tirzepatide Program
$524/mo total
Medications: Compounded Tirzepatide
- Medication
- Membership
- Lab Work
- Clinician Access
Mayo Clinic Diet Programs
Companion Subscription
$49.99/mo (diet support only)
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
Clinical Subscription
$99.99/mo + $99.99 start fee + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Visits Via Amwell
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
- Exercise Program
Ratings Breakdown
| Category | Hone Health | Mayo Clinic Diet |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Mayo Clinic Diet edges out Hone Health with a ClearScore of 78 vs 77. Mayo Clinic Diet is more affordable starting at $50/mo compared to $185/mo. For customer support, Hone Health rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.