HormoneSynergy vs Sesame: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
HormoneSynergy starts at $300/mo and Sesame at $99/mo. Sesame scores higher on our ClearScore (70 vs 74), and Sesame is the cheaper starting option.
Quick Verdict
Sesame has the higher ClearScore (74 vs 70)
Sesame is more affordable ($99/mo vs $300/mo)
HormoneSynergy has higher ratings (4.6/5 vs 4.1/5)
Sesame scores better on value (4.3/5 vs 4.1/5)
HormoneSynergy
$300/mo
starting price
Longevity-focused GLP-1 program with DEXA scans, CGM, and hormone optimization in Portland, OR.
Sesame
$99/mo
starting price
Wide medication selection with 14 options, insurance navigation support, and same-day consultations starting at $99/month.
HormoneSynergy vs Sesame: Full Comparison
| HormoneSynergy | Sesame | |
|---|---|---|
| ClearScore | 70/100 | 74/100 ✓ |
| Overall Rating | 4.6/5 ✓ | 4.1/5 |
| Review Count | 42 | 156 ✓ |
| Starting Price | $300/mo | $99/mo ✓ |
| Medications | Semaglutide, Tirzepatide | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Metformin, Contrave ✓ |
| Telehealth | No | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Not accepted | Accepted |
| Founded | 2006 | 2018 |
| States Served | 1 states | All 50 states |
Programs & Pricing
HormoneSynergy Programs
Weight Loss for Longevity
From $300/mo
Medications: Semaglutide, Tirzepatide
- Medication
- Dexa Scans
- Cgm Monitoring
- Hormone Optimization
Sesame Programs
Success by Sesame
$99/mo + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Consultations
- Labs Included
- Insurance Navigation
- Same Day Appointments
Ratings Breakdown
| Category | HormoneSynergy | Sesame |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Sesame edges out HormoneSynergy with a ClearScore of 74 vs 70. Sesame is more affordable starting at $99/mo compared to $300/mo. For customer support, HormoneSynergy rates higher (4.7/5). The best choice depends on your priorities, medication preferences, and budget.