Best Online GLP-1 Programs in 2026: Ro vs Hims vs MEDVi vs Found

By the Clear Metabolic team — personally on Mounjaro since 2024. Last updated February 2026.

Disclosure: I am not a doctor. I write about GLP-1 medications based on my personal experience as a Mounjaro patient and my own research. Nothing on this site is medical advice. Always talk to your doctor before starting, stopping, or changing any medication. This site earns commissions from telehealth providers linked on this page. Full disclaimer

I’ve spent the better part of two years deep in the GLP-1 world. I started Mounjaro through my endocrinologist, but along the way I’ve researched every major online provider obsessively — reading forums, comparing pricing pages, talking to people who’ve used them, and in some cases signing up myself to test the onboarding experience.

The online GLP-1 space has exploded. There are now dozens of telehealth platforms promising to get you on semaglutide or tirzepatide with a quick questionnaire and a video call. Some are excellent. Some are glorified prescription mills. And the pricing? It’s all over the place.

This guide breaks down the 8 best online GLP-1 programs available right now, with honest assessments of what you actually get for your money. No fluff, no rankings bought by the highest affiliate payout — just what I’d tell a friend who asked me where to start.

TL;DR — Quick Picks

Not everyone has time for 3,000 words. Here are the highlights:

How We Evaluated These Programs

Choosing a GLP-1 program isn’t just about who has the lowest price. After researching all of these platforms, here’s what actually matters:

Price

What do you pay monthly? Are there hidden fees — enrollment costs, lab fees, shipping? I list the all-in monthly cost as accurately as possible, but note that pricing in this space changes frequently. Always verify on the provider’s site before committing.

Medication Options

Does the platform offer semaglutide, tirzepatide, or both? Compounded or brand-name? Compounded versions are significantly cheaper but are produced by compounding pharmacies rather than the original manufacturer. As of early 2026, the FDA’s stance on compounded GLP-1s continues to evolve — something worth keeping on your radar.

Clinician Access

Can you message your prescribing clinician? How quickly do they respond? Is there a dedicated provider or a rotating pool? This matters more than you think, especially during dose titration.

Coaching & Behavioral Support

A GLP-1 alone won’t fix your relationship with food. Programs that include nutrition guidance, habit coaching, or structured behavior change tend to produce better long-term outcomes.

User Experience

How easy is onboarding? Is the app well-designed? How’s the shipping? These “soft” factors affect whether you stick with a program month after month.

Provider Reviews

1. Ro — Best Overall Value

Monthly Cost: ~$149/mo Program Name: GLP-1 Body Program Medications: Compounded semaglutide Coaching: Ongoing clinical support (not dedicated 1:1 coaching) Lab Work: Metabolic labs included

Ro has quietly become one of the most credible telehealth platforms in the country. Their GLP-1 Body Program pairs compounded semaglutide with metabolic lab work — something most competitors charge extra for or skip entirely.

What I like about Ro is the lack of gimmicks. You get a clinical evaluation, metabolic labs to establish a baseline, your medication shipped to your door, and ongoing support from their clinical team. The labs are a genuine differentiator at this price point. Most programs at $149/mo are medication-only.

What’s Included:

Pros:

Cons:

Best For: Someone who wants a clinically grounded program with lab work at a fair price, and doesn’t need hand-holding on the behavior side.

Metabolic labs + compounded semaglutide from $149/mo

Try Ro →

2. Hims / Hers — Best App Experience

Monthly Cost: ~$199/mo Medications: Compounded semaglutide Coaching: In-app guidance and content Lab Work: Not included (recommended separately)

Hims and Hers (same parent company, separate brands) have the most polished consumer experience in telehealth. If you’ve used their platform for anything else — hair loss, skincare, mental health — you know what to expect: clean design, fast onboarding, and a genuinely good app.

Their GLP-1 program offers compounded semaglutide at $199/mo. That’s $50 more than Ro without included labs, so you’re paying a premium for the brand and the app experience. Whether that’s worth it depends on how much you value a smooth digital experience and a platform you’re already comfortable with.

What’s Included:

Pros:

Cons:

Best For: Someone who values a premium digital experience and wants to manage everything from a well-designed app. Good choice if you’re already a Hims/Hers customer.

GLP-1 weight loss with the best app in telehealth

Try Hims/Hers →

3. MEDVi — Best for Tirzepatide

Monthly Cost: ~$249/mo Medications: Compounded tirzepatide Coaching: Clinical support with body composition focus Lab Work: Body composition tracking included

If you’ve done your homework on GLP-1s, you know that tirzepatide (the molecule in Mounjaro and Zepbound) is the newer, dual-action option that targets both GLP-1 and GIP receptors. Clinical trials consistently show it edges out semaglutide on weight loss outcomes.

MEDVi has carved out a niche as the go-to platform for compounded tirzepatide. At $249/mo they’re not cheap, but they’re one of the few programs that leads with tirzepatide rather than treating it as an afterthought. Their body composition tracking is a nice touch — weight alone doesn’t tell the full story, and tracking lean mass vs. fat mass gives you a much better picture of what’s actually happening.

What’s Included:

Pros:

Cons:

Best For: Someone who specifically wants tirzepatide and cares about body composition, not just the number on the scale. Worth the premium if tirzepatide is your target medication.

Compounded tirzepatide with body composition tracking

Try MEDVi →

4. Found Health — Best Budget + Coaching Combo

Monthly Cost: ~$129/mo Medications: Compounded semaglutide and other weight loss medications Coaching: Behavior coaching with board-certified obesity medicine doctors Lab Work: Not included

Found takes a different approach than most GLP-1 programs. Instead of leading with medication alone, they pair prescriptions with genuine behavior coaching — and their clinical team includes board-certified obesity medicine specialists, not just general practitioners who added weight loss to their services page.

At $129/mo, Found is the most affordable program on this list. The trade-off is that lab work isn’t included and their platform isn’t as polished as Hims or Ro. But if you’re looking for a program that treats the behavioral side of weight loss as seriously as the medication side, Found is hard to beat at this price.

What’s Included:

Pros:

Cons:

Best For: Budget-conscious individuals who want a program that takes behavior change seriously. Ideal if you know medication alone won’t be enough and you want real coaching support.

GLP-1 + behavior coaching from board-certified specialists -- $129/mo

Try Found Health →

5. Calibrate — Best Structured Program

Monthly Cost: ~$159/mo + $249 one-time membership fee Program Name: Metabolic Reset Medications: GLP-1 medications (semaglutide and tirzepatide, subject to availability) Coaching: Dedicated 1:1 coaching, structured 1-year program Lab Work: Metabolic labs included

Calibrate is the most structured program on this list. Their “Metabolic Reset” is a full year-long commitment that combines GLP-1 medication with dedicated coaching, metabolic lab work, and a curriculum built around food, sleep, exercise, and emotional health.

The upfront $249 membership fee plus $159/mo makes Calibrate the priciest option when you factor in total first-year cost (roughly $2,157). But the structure is unmatched. You’re not just getting a prescription and a “good luck” — you’re getting a year-long guided program with accountability built in.

I haven’t gone through the full Calibrate program myself, but people I’ve spoken to who completed the year consistently say the coaching and structure were what made the difference, especially for maintaining results after stepping down their dose.

What’s Included:

Pros:

Cons:

Best For: Someone who wants the most comprehensive, structured approach and is willing to commit to a year-long program. Best if you’ve tried “just medication” before and know you need accountability.

A full year metabolic reset -- medication, coaching, and labs

Try Calibrate →

6. Shed — Best No-Frills Option

Monthly Cost: ~$149/mo Medications: Compounded semaglutide Coaching: Minimal — clinical support only Lab Work: Not included

Shed is exactly what it sounds like. No elaborate coaching programs, no gamified apps, no community forums. You get evaluated by a clinician, receive compounded semaglutide if appropriate, and manage your treatment with straightforward clinical check-ins.

For some people, this is exactly right. Not everyone wants or needs a behavior change program wrapped around their prescription. If you’ve already dialed in your nutrition and exercise habits and you just need affordable access to medication with clinical oversight, Shed delivers without the extras.

What’s Included:

Pros:

Cons:

Best For: Self-directed individuals who’ve done their research, have their habits in order, and just want efficient, affordable access to compounded semaglutide.

Straightforward GLP-1 access -- no extras, no upsells

Try Shed →

7. Eden — Solid Middle Ground

Monthly Cost: ~$179/mo Medications: Multiple options including compounded semaglutide and tirzepatide Coaching: Clinical support with some lifestyle guidance Lab Work: Available but may cost extra

Eden positions itself as a telehealth weight loss platform with flexibility. Unlike some competitors that lock you into one medication, Eden evaluates you for multiple GLP-1 options and other weight loss medications, then works with you to find the right fit.

The $179/mo price point puts Eden in the middle of the pack. You get more medication flexibility than Ro or Hims, but less structure than Calibrate and less specialization than MEDVi. It’s a solid generalist option.

What’s Included:

Pros:

Cons:

Best For: Someone who wants flexibility in medication options and prefers a middle-of-the-road approach — not the cheapest, not the most expensive, not the most structured, but solid across the board.

Flexible GLP-1 prescriptions with multiple medication options

Try Eden →

8. SkyRx — Best Premium / High-Touch

Monthly Cost: ~$299/mo Medications: Compounded semaglutide and tirzepatide Coaching: High-touch clinical team Lab Work: Comprehensive labs included

SkyRx is the premium play. At $299/mo, it’s the most expensive program on this list, but you get the most comprehensive clinical package: full metabolic lab panels, the highest level of clinician interaction, access to both semaglutide and tirzepatide, and a clinical team that actively manages your case rather than waiting for you to reach out.

Think of SkyRx as the concierge medicine of online GLP-1 programs. If you want a provider who proactively checks in, adjusts your protocol based on labs, and treats your weight loss as a serious medical intervention rather than a subscription box, this is the tier.

I haven’t personally used SkyRx, but the people I’ve spoken to who have tend to be folks who tried a budget option first, felt unsupported, and were willing to pay more for a higher-touch experience.

What’s Included:

Pros:

Cons:

Best For: Someone with complex metabolic health needs, a history of metabolic conditions, or anyone who wants the highest level of clinical oversight. Also good for people who tried a lower-cost option and felt like they were just getting a prescription without real medical guidance.

Premium GLP-1 program -- comprehensive labs and proactive clinical care

Try SkyRx →

Side-by-Side Comparison

Provider Monthly Price Medications Coaching Lab Work App
Ro $149/mo Compounded semaglutide Clinical support Included Good
Hims/Hers $199/mo Compounded semaglutide In-app content Not included Excellent
MEDVi $249/mo Compounded tirzepatide Clinical + body comp Body comp tracking Good
Found Health $129/mo Semaglutide + others 1:1 behavior coaching Not included Basic
Calibrate $159/mo + $249 fee Semaglutide or tirzepatide Dedicated 1:1 coach Included Good
Shed $149/mo Compounded semaglutide Minimal Not included Basic
Eden $179/mo Semaglutide + tirzepatide Lifestyle guidance Available (extra cost) Good
SkyRx $299/mo Semaglutide + tirzepatide High-touch clinical Comprehensive Good

Pricing is approximate and may vary. Always verify current pricing on the provider’s website. Prices reflect medication + program costs and do not include potential insurance reimbursement.

How to Choose: A Decision Tree

Still not sure? Walk through these questions:

“What’s my budget?”

“Do I specifically want tirzepatide?”

“How much support do I need?”

“Do I want lab work included?”

“How long do I want to commit?”

The Bottom Line

There’s no single “best” GLP-1 program — it depends on what you need, what you can afford, and how much support you want around the medication.

If I had to pick one recommendation for most people, it would be Ro. At $149/mo with included metabolic labs, it hits the sweet spot of clinical credibility, fair pricing, and enough support without unnecessary bloat. It’s the program I’d point a friend toward if they asked me “where do I start?”

If budget is the top concern, Found Health at $129/mo with genuine behavior coaching is remarkable value. If you specifically want tirzepatide, MEDVi is the specialist. And if you know you need structure and accountability to succeed long-term, Calibrate’s year-long metabolic reset is worth the investment.

One thing I want to be transparent about: I’m personally on brand-name Mounjaro through my endocrinologist, not through any of these platforms. I’ve researched all of them extensively, tested several onboarding flows, and talked to real users — but I haven’t completed a full treatment cycle through each one. My recommendations are based on thorough research, not personal use of every single program.

The GLP-1 space is moving fast. Compounding pharmacy regulations, new medications entering the market, and insurance coverage changes mean the picture in six months may look different. I’ll keep this page updated as things evolve.

Whatever you choose, the most important thing is to start. These medications work. The data is overwhelming. And having clinical support — whether minimal or comprehensive — is always better than going it alone.

Frequently Asked Questions

Are these compounded GLP-1 medications safe?

Compounded medications are prepared by licensed compounding pharmacies and prescribed by licensed clinicians. They contain the same active ingredient (semaglutide or tirzepatide) as the brand-name versions. However, they are not FDA-approved in the same way brand-name drugs are. The FDA has taken evolving positions on compounded GLP-1s — it’s worth staying informed on current regulations. All programs listed here work with licensed pharmacies and licensed prescribers.

Can I use insurance with these programs?

Most of these programs operate on a cash-pay model and do not bill insurance directly. Some may provide documentation you can submit for potential reimbursement, but coverage varies widely by plan. If insurance coverage is important to you, check with your insurance provider and ask each platform about their specific policies.

How quickly will I see results?

Most people notice appetite changes within the first 1-2 weeks. Meaningful weight loss typically begins within the first month, with significant results at the 3-6 month mark. Individual results vary based on starting weight, dosage, diet, exercise, and other factors. GLP-1 medications are not magic — they work best when combined with healthy habits.

What happens if I stop taking the medication?

This is the million-dollar question in the GLP-1 space. Research shows that many people regain some weight after stopping GLP-1 medications, which is why programs that include behavior coaching (like Found and Calibrate) may offer better long-term outcomes. The habits you build while on medication matter as much as the medication itself.

Which is better — semaglutide or tirzepatide?

Clinical data suggests tirzepatide (the molecule in Mounjaro/Zepbound) produces slightly greater average weight loss than semaglutide (Ozempic/Wegovy) in head-to-head trials. However, individual responses vary. Some people respond better to semaglutide, others to tirzepatide. Side effect profiles are similar. If you have a preference, choose a program that offers your preferred medication. If you’re unsure, starting with semaglutide (more widely available, often cheaper) and switching if needed is a reasonable approach.

Are there side effects?

The most common side effects of GLP-1 medications are gastrointestinal: nausea, constipation, diarrhea, and decreased appetite (which is, in a way, the point). These are typically most pronounced during dose titration and often improve over time. More serious but rare side effects exist — your prescribing clinician should review these with you. Never start a GLP-1 medication without proper medical evaluation.

Can I switch between programs?

Yes. Most of these programs are month-to-month subscriptions (Calibrate being the exception with its year-long commitment). If you start with one program and it’s not working for you, you can cancel and sign up with another. Your new provider will do their own clinical evaluation. Keep records of your dose history and any lab results to share with your new provider.

Do I need to diet and exercise while on a GLP-1?

GLP-1 medications reduce appetite and can change your relationship with food, but they work best alongside healthy eating and regular physical activity. You don’t need to follow a strict diet, but prioritizing protein (to preserve muscle mass), staying hydrated, and incorporating resistance training will significantly improve your results and how you feel.

Clear Metabolic is an independent review site. We may earn a commission if you sign up through our links, at no extra cost to you. This helps us keep the site running and our reviews honest. All opinions are our own. We are not medical professionals — always consult with a licensed healthcare provider before starting any medication. Pricing listed is approximate as of February 2026 and may change without notice.