Genesis Lifestyle Medicine vs Mayo Clinic Diet: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Genesis Lifestyle Medicine starts at $150/mo and Mayo Clinic Diet at $50/mo. Mayo Clinic Diet scores higher on our ClearScore (72 vs 78), and Mayo Clinic Diet is the cheaper starting option.
Quick Verdict
Mayo Clinic Diet has the higher ClearScore (78 vs 72)
Mayo Clinic Diet is more affordable ($50/mo vs $150/mo)
Genesis Lifestyle Medicine scores better on value (4.2/5 vs 3.8/5)
Genesis Lifestyle Medicine
$150/mo
starting price
20+ locations across 9 states with physician-supervised GLP-1 programs targeting 15-20% body weight loss.
Mayo Clinic Diet
$50/mo
starting price
World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.
Genesis Lifestyle Medicine vs Mayo Clinic Diet: Full Comparison
| Genesis Lifestyle Medicine | Mayo Clinic Diet | |
|---|---|---|
| ClearScore | 72/100 | 78/100 ✓ |
| Overall Rating | 4.4/5 | 4.4/5 |
| Review Count | 89 | 98 ✓ |
| Starting Price | $150/mo | $50/mo ✓ |
| Medications | Semaglutide, Tirzepatide, Phentermine | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide |
| Telehealth | No | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2015 | 1889 |
| States Served | 9 states | All 50 states |
Programs & Pricing
Genesis Lifestyle Medicine Programs
Medical Weight Loss
From $150/mo
Medications: Semaglutide, Tirzepatide, Phentermine
- Medication
- Clinician Support
- Dietary Consultation
Mayo Clinic Diet Programs
Companion Subscription
$49.99/mo (diet support only)
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
Clinical Subscription
$99.99/mo + $99.99 start fee + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Visits Via Amwell
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
- Exercise Program
Ratings Breakdown
| Category | Genesis Lifestyle Medicine | Mayo Clinic Diet |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Mayo Clinic Diet edges out Genesis Lifestyle Medicine with a ClearScore of 78 vs 72. Mayo Clinic Diet is more affordable starting at $50/mo compared to $150/mo. For customer support, Genesis Lifestyle Medicine rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.