Mayo Clinic Diet vs Medi-Weightloss: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Mayo Clinic Diet starts at $50/mo and Medi-Weightloss at $399/mo. Mayo Clinic Diet scores higher on our ClearScore (78 vs 74), and Mayo Clinic Diet is the cheaper starting option.
Quick Verdict
Mayo Clinic Diet has the higher ClearScore (78 vs 74)
Mayo Clinic Diet is more affordable ($50/mo vs $399/mo)
Mayo Clinic Diet has higher ratings (4.4/5 vs 4.2/5)
Mayo Clinic Diet scores better on value (3.8/5 vs 3.5/5)
Mayo Clinic Diet
$50/mo
starting price
World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.
Medi-Weightloss
$399/mo
starting price
National franchise with 100+ clinics offering physician-supervised GLP-1 programs, nutrition counseling, and metabolic testing.
Mayo Clinic Diet vs Medi-Weightloss: Full Comparison
| Mayo Clinic Diet | Medi-Weightloss | |
|---|---|---|
| ClearScore | 78/100 ✓ | 74/100 |
| Overall Rating | 4.4/5 ✓ | 4.2/5 |
| Review Count | 98 | 342 ✓ |
| Starting Price | $50/mo ✓ | $399/mo |
| Medications | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide ✓ | Branded Semaglutide, Branded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 1889 | 2007 |
| States Served | All 50 states | 19 states |
Programs & Pricing
Mayo Clinic Diet Programs
Companion Subscription
$49.99/mo (diet support only)
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
Clinical Subscription
$99.99/mo + $99.99 start fee + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Visits Via Amwell
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
- Exercise Program
Medi-Weightloss Programs
Signature Program
$399/mo
Medications: Branded Semaglutide, Branded Tirzepatide
- Medication
- In Person Visits
- Nutrition Counseling
- Metabolic Testing
- Body Composition
Ratings Breakdown
| Category | Mayo Clinic Diet | Medi-Weightloss |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Mayo Clinic Diet edges out Medi-Weightloss with a ClearScore of 78 vs 74. Mayo Clinic Diet is more affordable starting at $50/mo compared to $399/mo. For customer support, Medi-Weightloss rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.