Mayo Clinic Diet vs PlushCare: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Mayo Clinic Diet starts at $50/mo and PlushCare at $20/mo. Mayo Clinic Diet scores higher on our ClearScore (78 vs 70), and PlushCare is the cheaper starting option.
Quick Verdict
Mayo Clinic Diet has the higher ClearScore (78 vs 70)
PlushCare is more affordable ($20/mo vs $50/mo)
Mayo Clinic Diet has higher ratings (4.4/5 vs 4/5)
Mayo Clinic Diet
$50/mo
starting price
World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.
PlushCare
$20/mo
starting price
Full-service virtual primary care with board-certified doctors prescribing brand-name GLP-1s and insurance billing.
Mayo Clinic Diet vs PlushCare: Full Comparison
| Mayo Clinic Diet | PlushCare | |
|---|---|---|
| ClearScore | 78/100 ✓ | 70/100 |
| Overall Rating | 4.4/5 ✓ | 4/5 |
| Review Count | 98 | 174 ✓ |
| Starting Price | $50/mo | $20/mo ✓ |
| Medications | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Contrave ✓ |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 1889 | 2014 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Mayo Clinic Diet Programs
Companion Subscription
$49.99/mo (diet support only)
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
Clinical Subscription
$99.99/mo + $99.99 start fee + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Visits Via Amwell
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
- Exercise Program
PlushCare Programs
Weight Loss Program
$19.99/mo + consults + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Membership Access
- Prescription Discount Card
- Provider Messaging
Ratings Breakdown
| Category | Mayo Clinic Diet | PlushCare |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Mayo Clinic Diet edges out PlushCare with a ClearScore of 78 vs 70. PlushCare is more affordable starting at $20/mo compared to $50/mo. For customer support, Mayo Clinic Diet rates higher (4.3/5). The best choice depends on your priorities, medication preferences, and budget.