SkyRx vs Yucca Health: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
SkyRx starts at $299/mo and Yucca Health at $146/mo. SkyRx scores higher on our ClearScore (75 vs 72), and Yucca Health is the cheaper starting option.
Quick Verdict
SkyRx has the higher ClearScore (75 vs 72)
Yucca Health is more affordable ($146/mo vs $299/mo)
Yucca Health has higher ratings (4.6/5 vs 4.4/5)
Yucca Health scores better on value (4.6/5 vs 3.6/5)
SkyRx
$299/mo
starting price
Premium GLP-1 program with full labs, high-touch clinician access, and both semaglutide and tirzepatide.
Yucca Health
$146/mo
starting price
Compounded GLP-1s from $146/mo. 50-state telehealth, 2-day shipping, 20K+ patients, LegitScript verified.
SkyRx vs Yucca Health: Full Comparison
| SkyRx | Yucca Health | |
|---|---|---|
| ClearScore | 75/100 ✓ | 72/100 |
| Overall Rating | 4.4/5 | 4.6/5 ✓ |
| Review Count | 58 | 20,000 ✓ |
| Starting Price | $299/mo | $146/mo ✓ |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Not accepted |
| Founded | 2022 | 2023 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
SkyRx Programs
Premium Weight Loss
$299/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Full Labs
- Dedicated Clinician
- Priority Support
Yucca Health Programs
Semaglutide Program
From $146/mo (6-month plan)
Medications: Compounded Semaglutide
- Medication
- Consultation
- Supplies
- Shipping
Tirzepatide Program
From $258/mo (6-month plan)
Medications: Compounded Tirzepatide
- Medication
- Consultation
- Supplies
- Shipping
Ratings Breakdown
| Category | SkyRx | Yucca Health |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
SkyRx edges out Yucca Health with a ClearScore of 75 vs 72. Yucca Health is more affordable starting at $146/mo compared to $299/mo. For customer support, SkyRx rates higher (4.8/5). The best choice depends on your priorities, medication preferences, and budget.